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Christopher J Buckley Selected Research

flutemetamol

3/2024Association Between Years of Education and Amyloid Burden in Patients With Subjective Cognitive Decline, MCI, and Alzheimer Disease.
1/2021Visual assessment of [18F]flutemetamol PET images can detect early amyloid pathology and grade its extent.
11/2020Derivation and utility of an Aβ-PET pathology accumulation index to estimate Aβ load.
10/2020Post-mortem analyses of PiB and flutemetamol in diffuse and cored amyloid-β plaques in Alzheimer's disease.
4/2018Validation of prognostic biomarker scores for predicting progression of dementia in patients with amnestic mild cognitive impairment.
1/2018Use of Flutemetamol F 18-Labeled Positron Emission Tomography and Other Biomarkers to Assess Risk of Clinical Progression in Patients With Amnestic Mild Cognitive Impairment.
1/2017Performance of [18F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA-AA recommendations for the neuropathologic diagnosis of Alzheimer's disease.
3/2015Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density.

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Christopher J Buckley Research Topics

Disease

8Alzheimer Disease (Alzheimer's Disease)
03/2024 - 03/2015
5Cognitive Dysfunction
03/2024 - 01/2018
4Amyloid Plaque
01/2021 - 03/2015
3Death (Near-Death Experience)
11/2020 - 03/2015
2Dementia (Dementias)
01/2022 - 04/2018
1Disease Progression
01/2018

Drug/Important Bio-Agent (IBA)

8flutemetamolIBA
03/2024 - 03/2015
8Amyloid (Amyloid Fibrils)IBA
03/2024 - 03/2015
3Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2018
13- (3,5- dichlorophenyl)- 1- methyl- 2,5- pyrrolidinedione (DPMS)IBA
03/2024
14- (N- methylamino)- 4'- (2- (2- (2- fluoroethoxy)ethoxy)ethoxy)stilbeneIBA
03/2024
1florbetapirIBA
11/2020
1FluorineIBA
03/2015